Structure of PDB 9f1l Chain A

Receptor sequence
>9f1lA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTE
3D structure
PDB9f1l First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 35
ChainA
Resolution1.30001 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H83 A W81 P82 F83 Q85 L92 I146 W40 P41 F42 Q44 L51 I105
External links
PDB RCSB:9f1l, PDBe:9f1l, PDBj:9f1l
PDBsum9f1l
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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