Structure of PDB 9f1j Chain A

Receptor sequence
>9f1jA (length=124) Species: 9606 (Homo sapiens) [Search protein sequence]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPT
3D structure
PDB9f1j First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 14
ChainA
Resolution1.13003 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 A1H84 A W81 P82 K91 L92 N140 I146 W39 P40 K49 L50 N98 I104
External links
PDB RCSB:9f1j, PDBe:9f1j, PDBj:9f1j
PDBsum9f1j
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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