Structure of PDB 9ez3 Chain A

Receptor sequence
>9ez3A (length=335) Species: 9606 (Homo sapiens) [Search protein sequence]
VEDDKEGHLVCRIGDWLQERYEIVGNLGEGTFGKVVECLDHARGKSQVAL
KIIRNVGKYREAARLEINVLKKIKEKDKENKFLCVLMSDWFNFHGHMCIA
FELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALRFLHENQLTHTDLK
PENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGIVATRHYRPPEVI
LELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGPIPSH
MIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLF
DLMRRMLEFDPAQRITLAEALLHPFFAGLTPEERS
3D structure
PDB9ez3 Crystal structure of human CLK3 bound to RN129
ChainA
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H74 A E201 V220 F236 E237 L238 L239 L290 V318 A319 D320 F321 E66 V85 F101 E102 L103 L104 L155 V183 A184 D185 F186
External links
PDB RCSB:9ez3, PDBe:9ez3, PDBj:9ez3
PDBsum9ez3
PubMed
UniProtP49761|CLK3_HUMAN Dual specificity protein kinase CLK3 (Gene Name=CLK3)

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