Structure of PDB 9ey6 Chain A

Receptor sequence
>9ey6A (length=447) Species: 9606 (Homo sapiens) [Search protein sequence]
QFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRCEAVTADSRP
HSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQ
RVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDG
NTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWH
RYHLLRLEKDMQEMLQEPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDS
TLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMV
QRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVEGYSDPTGKYDPAVR
SLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADIST
FPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSR
3D structure
PDB9ey6 Interactions of phenylalanine derivatives with human tyrosinase: lessons from experimental and theoretical studies.
ChainA
Resolution2.228 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.18.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC A G39 R93 G15 R69
BS02 ZN A H192 H215 H224 H168 H191 H200
BS03 ZN A H377 H381 H404 H353 H357 H380
BS04 ZN A H75 H81 E88 H51 H57 E64
BS05 ZN A H143 E241 H119 E217
External links
PDB RCSB:9ey6, PDBe:9ey6, PDBj:9ey6
PDBsum9ey6
PubMed38642076
UniProtP17643|TYRP1_HUMAN 5,6-dihydroxyindole-2-carboxylic acid oxidase (Gene Name=TYRP1)

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