Structure of PDB 9ey5 Chain A

Receptor sequence
>9ey5A (length=447) Species: 9606 (Homo sapiens) [Search protein sequence]
QFPRQCATVEALRSGMCCPDLSPVSGPGTDRCGSSSGRGRCEAVTADSRP
HSPQYPHDGRDDREVWPLRFFNRTCHCNGNFSGHNCGTCRPGWRGAACDQ
RVLIVRRNLLDLSKEEKNHFVRALDMAKRTTHPLFVIATRRSEEILGPDG
NTPQFENISIYNYFVWTHYYSVKKTFLGVGQESFGEVDFSHEGPAFLTWH
RYHLLRLEKDMQEMLQEPSFSLPYWNFATGKNVCDICTDDLMGSRSNFDS
TLISPNSVFSQWRVVCDSLEDYDTLGTLCNSTEDGPIRRNPAGNVARPMV
QRLPEPQDVAQCLEVGLFDTPPFYSNSTNSFRNTVEGYSDPTGKYDPAVR
SLHNLAHLFLNGTGGQTHLSPNDPIFVLLHTFTDAVFDEWLRRYNADIST
FPLENAPIGHNRQYNMVPFWPPVTNTEMFVTAPDNLGYTYEIQWPSR
3D structure
PDB9ey5 Interactions of phenylalanine derivatives with human tyrosinase: lessons from experimental and theoretical studies.
ChainA
Resolution2.61 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.14.18.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 OTY A H377 N378 H381 G389 T391 S394 H353 N354 H357 G365 T367 S370
BS02 ZN A H192 H215 H224 H168 H191 H200
BS03 ZN A H377 H381 H404 H353 H357 H380
BS04 ZN A E66 H100 E42 H76
BS05 ZN A H75 H81 E88 H51 H57 E64
External links
PDB RCSB:9ey5, PDBe:9ey5, PDBj:9ey5
PDBsum9ey5
PubMed38642076
UniProtP17643|TYRP1_HUMAN 5,6-dihydroxyindole-2-carboxylic acid oxidase (Gene Name=TYRP1)

[Back to BioLiP]