Structure of PDB 9ey4 Chain A

Receptor sequence
>9ey4A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
GAPATVTEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLS
NGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEIAHLLIKPEYA
YGSAGSLPKIPSNATLFFEIELLDFKG
3D structure
PDB9ey4 Structure-Based Design of Ultrapotent Tricyclic Ligands for FK506-Binding proteins.
ChainA
Resolution1.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.2.1.8: peptidylprolyl isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1H78 A Y47 F57 D58 F67 Q75 V76 W80 Y103 S108 F120 Y45 F55 D56 F65 Q73 V74 W78 Y101 S106 F118
External links
PDB RCSB:9ey4, PDBe:9ey4, PDBj:9ey4
PDBsum9ey4
PubMed38837733
UniProtQ13451|FKBP5_HUMAN Peptidyl-prolyl cis-trans isomerase FKBP5 (Gene Name=FKBP5)

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