Structure of PDB 9eu5 Chain A

Receptor sequence
>9eu5A (length=785) Species: 10116 (Rattus norvegicus) [Search protein sequence]
GSCKGRCFELQEAGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKD
RCGEVRNEENACHCSEDCLSRGDCCTNYQVVCKGESHWVDDDCEEIKVPE
CPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYMRPVY
PTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWG
GQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAF
YSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIF
VGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPK
TIIAALTCKKPDQHFKPYMKQHLPKRLHYANNRRIEDIHLLVDRRWHVAR
KPLDVYKKPSGKCFFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFEN
IELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFRPTMPDEVSRPNYPGI
MYLQSEFDLGCTCDKGSAKERHLLYGRPAVLYRTSYDILYHTDFESGYSE
IFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSPGFSQNCLAYKNDK
QMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWAYFQRVLVKKY
ASERNGVNVISGPIFDYNYDGLRDTEDEIKQYVEGSSIPVPTHYYSIITS
CLDFTQPADKCDGPLSVSSFILPHRPDNDESCASSEDESKWVEELMKMHT
ARVRDIEHLTGLDFYRKTSRSYSEILTLKTYLHTY
3D structure
PDB9eu5 In situ serial crystallography facilitates 96-well plate structural analysis at low symmetry.
ChainA
Resolution3.0 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 5JK A L78 S81 Y214 K248 F249 H251 W254 P258 I261 F274 L23 S26 Y159 K193 F194 H196 W199 P203 I206 F219
BS02 ZN A R391 H444 R336 H389
BS03 ZN A D311 H315 H474 D256 H260 H419
BS04 ZN A D171 T209 D358 H359 D116 T154 D303 H304
BS05 CA A D739 N741 D743 L745 R746 D747 D666 N668 D670 L672 R673 D674
External links
PDB RCSB:9eu5, PDBe:9eu5, PDBj:9eu5
PDBsum9eu5
PubMed39008358
UniProtQ64610|ENPP2_RAT Autotaxin (Gene Name=Enpp2)

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