Structure of PDB 9eqg Chain A

Receptor sequence
>9eqgA (length=352) Species: 9606 (Homo sapiens) [Search protein sequence]
DNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDME
YTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVA
HNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGS
YAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGE
YVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFG
VTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY
FTKRGYAWDGKSVVPEKKTFNSVSKIDRLSRIAFPLLFGIFNLVYWATYL
NR
3D structure
PDB9eqg A brain-to-gut signal controls intestinal fat absorption.
ChainA
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PGW A K222 I239 K213 I230
BS02 PT5 A R249 S299 E303 F310 K312 R313 K326 N387 S388 S390 K391 I392 S396 F400 R240 S290 E294 F301 K303 R304 K317 N321 S322 S324 K325 I326 S330 F334
BS03 ABU A F65 R67 T130 F56 R58 T121
External links
PDB RCSB:9eqg, PDBe:9eqg, PDBj:9eqg
PDBsum9eqg
PubMed39261733
UniProtP14867|GBRA1_HUMAN Gamma-aminobutyric acid receptor subunit alpha-1 (Gene Name=GABRA1)

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