Structure of PDB 9enf Chain A

Receptor sequence
>9enfA (length=254) Species: 9606 (Homo sapiens) [Search protein sequence]
KRAFDFSAHGRRHVALRIAYMGWGYQGFASQENTNNTIEEKLFEALTKTR
LVESRQTSNYHRCGRTAKGVSAFGQVISLDLRSQFPEEIRYTHILNRVLP
PDIRILAWAPVEPSFSARFSCLERTYRYFFPRADLDIVTMDYAAQKYVGT
HDFRNLCKMDVANGVINFQRTILSAQVQLVQEPFQLCQFEVTGQAFLYHQ
VRCMMAILFLIEFPLVLYDCKDQEAQEFNITHLQQLWANHAVKTHMLYSM
LQGL
3D structure
PDB9enf The molecular basis of tRNA selectivity by human pseudouridine synthase 3.
ChainA
Resolution2.97 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A Q82 R116 A118 K119 Y276 H277 Q31 R65 A67 K68 Y198 H199
BS02 rna A K52 R53 A54 F55 K99 R166 V167 F343 K1 R2 A3 F4 K48 R97 V98 F228
Gene Ontology
Molecular Function
GO:0009982 pseudouridine synthase activity
GO:0016853 isomerase activity
GO:0160154 tRNA pseudouridine(38/39) synthase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0031119 tRNA pseudouridine synthesis
GO:1990481 mRNA pseudouridine synthesis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9enf, PDBe:9enf, PDBj:9enf
PDBsum9enf
PubMed38996458
UniProtQ9BZE2|PUS3_HUMAN tRNA pseudouridine(38/39) synthase (Gene Name=PUS3)

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