Structure of PDB 9ca1 Chain A

Receptor sequence
>9ca1A (length=612) Species: 9606 (Homo sapiens) [Search protein sequence]
VMKTVLMVAEMPSLAQSIAKILSRGSLSSHKGLNGACSVHEYTGTFAGQP
VRFKMTSVCGHVMTLDFLGKYNKWDKVDPAELFSQAPTEKKEANPKLNMV
KFLQVEGRGCDYIVLWLDCDKEGENICFEVLDAVLPVMNKAHGGEKTVFR
ARFSSITDTDICNAMACLGEPDHNEALSVDARQELDLRIGCAFTRFQTKY
FQGKYGDLDSSLISFGPCQTPTLGFCVERHDKIQSFKPETYWVLQAKVNT
DKDRSLLLDWDRVRVFDREIAQMFLNMTKLEKEAQVEATSRKEKAKQRPL
ALNTVEMLRVASSSLGMGPQHAMQTAERLYTQGYISYPRTETTHYPENFD
LKGSLRQQANHPYWADTVKRLLAEGINRPRKGHDAGDHPPITPMKSATEA
ELGGDAWRLYEYITRHFIATVSHDCKYLQSTISFRIGPELFTCSGKTVLS
PGFTEVMPWQSVPLEESLPTCQRGDAFPVGEVKMLEKQTNPPDYLTEAEL
ITLMEKHGIGTDASIPVHINNICQRNYVTVESGRRLKPTNLGIVLVHGYY
KIDAELVLPTIRSAVEKQLNLIAQGKADYRQVLGHTLDVFKRKFHYFVDS
IAGMDELMEVSF
3D structure
PDB9ca1 Structural Insights into human Topoisomerase 3-beta DNA and RNA catalytic cycles and topo-gate dynamics
ChainA
Resolution3.26 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H60 T63 N71 W73 R181 L186 G189 C190 R194 S213 F214 G215 Q218 Y336 T510 H517 H61 T64 N72 W74 R182 L187 G190 C191 R195 S214 F215 G216 Q219 Y337 T511 H518
BS02 dna A M10 A35 L96 E326 Y329 Y336 M11 A36 L97 E327 Y330 Y337
BS03 MN A E9 D117 Y336 E10 D118 Y337
BS04 MN A E340 D511 E341 D512
External links
PDB RCSB:9ca1, PDBe:9ca1, PDBj:9ca1
PDBsum9ca1
PubMed
UniProtO95985|TOP3B_HUMAN DNA topoisomerase 3-beta-1 (Gene Name=TOP3B)

[Back to BioLiP]