Structure of PDB 9c55 Chain A

Receptor sequence
>9c55A (length=288) Species: 9606 (Homo sapiens) [Search protein sequence]
PTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDV
SPYDHSRVKLQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMV
WQQKTKAVVMLNRIVEKESVKCAQYWPTDDQEMLFKETGFSVKLLSEDVK
SYYTVHLLQLENINSGETRTISHFHYTTWPDFGVPESPASFLNFLFKVRE
SGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGDDINIKQVLLNM
RKYRMGLIQTPDQLRFSYMAIIEGAKCQKRWKELSKED
3D structure
PDB9c55 Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites.
ChainA
Resolution2.36 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 527 A D31 Y48 K122 F183 S217 A218 I220 R222 G257 Q260 D30 Y47 K121 F182 S216 A217 I219 R221 G256 Q259
External links
PDB RCSB:9c55, PDBe:9c55, PDBj:9c55
PDBsum9c55
PubMed39177701
UniProtP17706|PTN2_HUMAN Tyrosine-protein phosphatase non-receptor type 2 (Gene Name=PTPN2)

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