Structure of PDB 9c3s Chain A

Receptor sequence

>9c3sA (length=250) Species: 95486 (Burkholderia cenocepacia) [Search protein sequence]

LPSGIELHNRDFLTDAAHLPDASIDLIVADPPYGLGKDYGNDSDKRSGDD
FLAWTREWLELAIPKLKPSGSMYIFCTWQYAPEIFSFLKTQLTMVNEIIW
DRRVPSMGGTTRRFTSVHDNIGFFAVSRAYYFDLDPVRIPYDADTKKARS
RKLFEGSKWLEMGYNPKDVWSVSRLHRQHAERVDHPTQKPLEIIERMVLA
SCPPGGRVLDPFMGSGTTAVACARQGRDFVGYEINESYCAIAHERVNALA

3D structure

PDB

9c3s Burkholderia cenocepacia epigenetic regulator M.BceJIV simultaneously engages two DNA recognition sequences for methylation.

Chain

Resolution

2.16 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	D59 P61 Y62 L64 K66 Y68 D73 T106 W107 S135 G137 T139 R141 R142 S145 D148 R203 H205 R206 R211 T216 K218	D30 P32 Y33 L35 K37 Y39 D44 T77 W78 S106 G108 T110 R112 R113 S116 D119 R174 H176 R177 R182 T187 K189
BS02	dna	A	R132 V133 P134 M136 G137 G138 T139 S202 H205 Q207 H208	R103 V104 P105 M107 G108 G109 T110 S173 H176 Q178 H179
BS03	dna	A	R167 Y170 R178 R180 F183 K187 W188 Y193 N194 K196	R138 Y141 R149 R151 F154 K158 W159 Y164 N165 K167
BS04	FRU	A	W107 Q108	W78 Q79
BS05	SFG	A	D40 D59 Y68 S72 H214 T216 F241 M242 S244 T246 Y261 E262 I263 Y267	D11 D30 Y39 S43 H185 T187 F212 M213 S215 T217 Y232 E233 I234 Y238

External links

PDB	RCSB:9c3s, PDBe:9c3s, PDBj:9c3s
PDBsum	9c3s
PubMed	39244607
UniProt	A0A8I1DKW0

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