Structure of PDB 9b70 Chain A

Receptor sequence
>9b70A (length=341) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
VLKYITFRSFTAVLIAFFLTLVLSPSFINRLRKIQRLFGGYVREYTPESH
EVKKYTPTMGGIVILIVVTLSTLLLMRWDIKYTWVVLLSFLSFGTIGFWD
DYVKLKNKKGISIKTKFLLQVLSASLISVLIYYWADIDTILYFPFFKELY
VDLGVLYLPFAVFVIVGSANAVNLTDGLDGLAIGPAMTTATALGVVAYAV
GHSKIAQYLNIPYVPYAGELTVFCFALVGAGLGFLWFNSFPAQMFMGDVG
SLSIGASLATVALLTKSEFIFAVAAGVFVFETISVILQIIYFRWTGGKRL
FKRAPFHHHLELNGLPEPKIVVRMWIISILLAIIAISMLKL
3D structure
PDB9b70 Development of a natural product optimization strategy for inhibitors against MraY, a promising antibacterial target.
ChainA
Resolution2.88 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1AI1 A K70 N190 D193 G194 L195 D196 F262 G264 T299 K53 N173 D176 G177 L178 D179 F245 G247 T282
Gene Ontology
Molecular Function
GO:0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity
GO:0016740 transferase activity
GO:0016780 phosphotransferase activity, for other substituted phosphate groups
GO:0042802 identical protein binding
GO:0046872 metal ion binding
GO:0051992 UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0044038 cell wall macromolecule biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:9b70, PDBe:9b70, PDBj:9b70
PDBsum9b70
PubMed38877016
UniProtO66465|MRAY_AQUAE Phospho-N-acetylmuramoyl-pentapeptide-transferase (Gene Name=mraY)

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