Structure of PDB 9b1o Chain A

Receptor sequence
>9b1oA (length=515) Species: 9606 (Homo sapiens) [Search protein sequence]
FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAP
LLDNSTAVSTSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATA
TSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAG
ILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFL
LAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGV
RDWTLLQLVVSVPFFLCFLYSWWLPESARWLIIKGKPDQALQELRKVARI
NGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPGLRFRTCISTLC
WFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRR
PTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYS
SELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPV
LSGLAALLLPETQSL
3D structure
PDB9b1o Transport mechanism and structural pharmacology of human urate transporter URAT1.
ChainA
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VGL A F238 S239 H242 F360 I381 D385 K389 L438 F236 S237 H240 F358 I379 D383 K387 L436
External links
PDB RCSB:9b1o, PDBe:9b1o, PDBj:9b1o
PDBsum9b1o
PubMed39245778
UniProtQ96S37|S22AC_HUMAN Solute carrier family 22 member 12 (Gene Name=SLC22A12)

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