Structure of PDB 9b1n Chain A

Receptor sequence

>9b1nA (length=515) Species: 9606 (Homo sapiens) [Search protein sequence]

FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAAVPSHRCWAP
LLDNSTAVSTSLSPEALLAISIPPGPNQRPHQCRRFRQPQWQLLDPNATA
TSWSEADTEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAG
ILVGAAACGPASDRFGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFL
LAFAVAGVMMNTGTLLMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGV
RDWTLLQLVVSVPFFLCFLYSWWLPESARWLIIKGKPDQALQELRKVARI
NGHKEAKNLTIEVLMSSVKEEVASAKEPRSVLDLFCVPGLRFRTCISTLC
WFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSHLGRR
PTLAASLLLAGLCILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYS
SELFPTVLRMTAVGLGQMAARGGAILGPLVRLLGVHGPWLPLLVYGTVPV
LSGLAALLLPETQSL

3D structure

PDB

9b1n Transport mechanism and structural pharmacology of human urate transporter URAT1.

Chain

Resolution

3.1 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	VGL	A	F238 K389 F445	F236 K387 F443

External links

PDB	RCSB:9b1n, PDBe:9b1n, PDBj:9b1n
PDBsum	9b1n
PubMed	39245778
UniProt	Q96S37\|S22AC_HUMAN Solute carrier family 22 member 12 (Gene Name=SLC22A12)

[Back to BioLiP]