Structure of PDB 9atn Chain A

Receptor sequence
>9atnA (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
GSARCAVCEGPGELCDLFFCTSCGHHYHGACLDTALTARKRAGWQCPECK
VCQACRKPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRV
3D structure
PDB9atn ASXLs binding to the PHD2/3 fingers of MLL4 provides a mechanism for the recruitment of BAP1 to active enhancers.
ChainA
ResolutionN/A
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V231 C255 L256 D257 P271 K274 D285 M288 V290 E292 A312 H313 S314 K316 V7 C31 L32 D33 P47 K50 D61 M64 V66 E68 A88 H89 S90 K92
BS02 ZN A C229 C232 H252 C5 C8 H28
BS03 ZN A C244 C247 C20 C23
BS04 ZN A C276 H299 C52 H75
BS05 ZN A C291 C317 C67 C93
External links
PDB RCSB:9atn, PDBe:9atn, PDBj:9atn
PDBsum9atn
PubMed38849395
UniProtO14686|KMT2D_HUMAN Histone-lysine N-methyltransferase 2D (Gene Name=KMT2D)

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