Structure of PDB 8zv9 Chain A

Receptor sequence

>8zv9A (length=266) Species: 9606 (Homo sapiens) [Search protein sequence]

SVDGSHSMRYFSTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEP
RAPWIEQEGPEYWDEETGKVKAHSQTDRENLRIALRYYNQSEAGSHTLQM
MFGCDVGSDGRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQITKRKW
EAAHVAEQQRAYLEGTCVDGLRRYLENGKETLQRTDPPKTHMTHHPLRCW
ALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVGEEQRYT
CHVQHEGLPKPLTLRW

3D structure

PDB

8zv9 Structural insights into immune escape at killer T cell epitope by SARS-CoV-2 Spike Y453F variants.

Chain

Resolution

2.6 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	Y7 E63 K66 V67 H70 T73 N77 Y84 F99 Y116 Y123 T143 W147 A150 V152 Q156 Y159 T163 Y171	Y10 E66 K69 V70 H73 T76 N80 Y87 F102 Y119 Y126 T146 W150 A153 V155 Q159 Y162 T166 Y174

External links

PDB	RCSB:8zv9, PDBe:8zv9, PDBj:8zv9
PDBsum	8zv9
PubMed	39002680
UniProt	A0A7T3RIT5

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