Structure of PDB 8zsz Chain A

Receptor sequence
>8zszA (length=315) Species: 9606 (Homo sapiens) [Search protein sequence]
GRNRGRLLCMLALTFMFMVLEVVVSRVTSSLAMLSDSFHMLSDVLALVVA
LVAERFARRTHATQKNTFGWIRAEVMGALVNAIFLTGLCFAILLEAIERF
IEPHEMQQPLVVLGVGVAGLLVNVLGLCLFHHGHSHGGHGHGHDRAGQLN
MRGVFLHVLGDALGSVIVVVNALVFYFSWKGCSEGDFCVNPCFPDPCKAY
EAGPCWVLYLDPTLCVVMVCILLYTTYPLLKESALILLQTVPKQIDIRNL
IKELRNVEGVEEVHELHVWQLAGSRIIATAHIKCEDPTSYMEVAKTIKDV
FHNHGIHATTIQPEF
3D structure
PDB8zsz Zinc transporter 1 functions in copper uptake and cuproptosis.
ChainA
Resolution3.59 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H370 E420 H264 E314
BS02 ZN A H43 D47 H251 D255 H39 D43 H157 D161
BS03 ZN A E371 H373 E265 H267
BS04 ZN A H153 H155 H408 H413 H139 H141 H302 H307
BS05 ZN A H146 H148 H132 H134
External links
PDB RCSB:8zsz, PDBe:8zsz, PDBj:8zsz
PDBsum8zsz
PubMed39111308
UniProtQ9Y6M5|ZNT1_HUMAN Proton-coupled zinc antiporter SLC30A1 (Gene Name=SLC30A1)

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