Structure of PDB 8zkd Chain A

Receptor sequence

>8zkdA (length=298) Species: 9606 (Homo sapiens) [Search protein sequence]

RDLDSALLAEVKDVLIPHERVVTHSDRVIGKGHFGVVYHGEYIDQAQNRI
QCAIKSLSRITEMQQVEAFLREGLLMRGLNHPNVLALIGIMLPPEGLPHV
LLPYMCHGDLLQFIRSPQRNPTVKDLISFGLQVARGMEYLAEQKFVHRDL
AARNCMLDESFTVKVADFGLARDILDREYYSVQQHRHARLPVKWTALESL
QTYRFTTKSDVWSFGVLLWELLTRGAPPYRHIDPFDLTHFLAQGRRLPQP
EYCPDSLYQVMQQCWEADPAVRPTFRVLVGEVEQIVSALLGDHYVQLP

3D structure

PDB

8zkd The Crystal Structure of the RON from Biortus.

Chain

Resolution

2.05 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ANP	A	I1088 G1089 G1091 H1092 V1096 A1112 K1114 Y1163 M1164 D1208 R1212 N1213 M1215 D1226	I29 G30 G32 H33 V37 A53 K55 Y104 M105 D149 R153 N154 M156 D167
BS02	MG	A	N1213 D1226	N154 D167

External links

PDB	RCSB:8zkd, PDBe:8zkd, PDBj:8zkd
PDBsum	8zkd
PubMed
UniProt	Q04912\|RON_HUMAN Macrophage-stimulating protein receptor (Gene Name=MST1R)

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