Structure of PDB 8zha Chain A

Receptor sequence
>8zhaA (length=143) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPSMNKELKKII
GQVRDQAEHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ
3D structure
PDB8zha Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety.
ChainA
Resolution1.95 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L1W A T124 T125 A128 T69 T70 A73
External links
PDB RCSB:8zha, PDBe:8zha, PDBj:8zha
PDBsum8zha
PubMed38942126
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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