Structure of PDB 8zh4 Chain A

Receptor sequence
>8zh4A (length=141) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACWWAGIKQEFGIPYNPSMNKELKKII
GQVRDQAEHLKTAVQMAVFIHNHKRGYSAGERIVDIIATDI
3D structure
PDB8zh4 Design and synthesis of novel and potent allosteric HIV-1 integrase inhibitors with a spirocyclic moiety.
ChainA
Resolution1.82 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L1V A A169 E170 H171 T174 A107 E108 H109 T112
External links
PDB RCSB:8zh4, PDBe:8zh4, PDBj:8zh4
PDBsum8zh4
PubMed38942126
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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