Structure of PDB 8zfo Chain A

Receptor sequence
>8zfoA (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
ESADLRALAKHLYDSYIKSFPLTKAKARAILTKSPFVIYDMNSLMMGEDK
IKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVH
EIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVK
FNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKL
NHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIY
3D structure
PDB8zfo Unanticipated mechanisms of covalent inhibitor and synthetic ligand cobinding to PPAR gamma.
ChainA
Resolution3.15 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NZA A I281 G284 R288 L330 L333 I341 S342 M348 I58 G61 R65 L107 L110 I118 S119 M125
External links
PDB RCSB:8zfo, PDBe:8zfo, PDBj:8zfo
PDBsum8zfo
PubMed
UniProtP37231|PPARG_HUMAN Peroxisome proliferator-activated receptor gamma (Gene Name=PPARG)

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