Structure of PDB 8yrs Chain A

Receptor sequence
>8yrsA (length=530) Species: 9606 (Homo sapiens) [Search protein sequence]
DSSPAAWNKEDFPWSGKVKDILQNVFKLEKFRPLQLETINVTMAGKEVFL
VMPTGGGKSLCYQLPALCSDGFTLVICPLISLMEDQLMVLKQLGISATML
NASSSKEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEAR
RFTRIAVDEVHCCSQWGHDFRPDYKALGILKRQFPNASLIGLTATATNHV
LTDAQKILCIEKCFTFTASFNRPNLYYEVRQKPSNTEDFIEDIVKLINGR
YKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWS
ANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMK
ADCILYYGFGDIFRISSMVVMENVGQQKLYEMVSYCQNISKCRRVLMAQH
FDEVWNSEACNKMCDNCCKSAFERKNITEYCRDLIKILKQAEELNEKLTP
LKLIDSWMGKGAAKLRVAGVVAPTLPREDLEKIIAHFLIQQYLKEDYSFT
AYATISYLKIGPKANLLNNEAHAITMQVTK
3D structure
PDB8yrs Crystal structure of human RECQ1 helicase containing a flexible linker in complex with tailed duplex DNA
ChainA
Resolution2.43 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A T521 L523 K524 Y579 T449 L451 K452 Y507
BS02 dna A F322 Q324 H345 A346 V372 A373 R425 M429 T572 Y574 A575 F261 Q263 H284 A285 V311 A312 R364 M368 T500 Y502 A503
BS03 ZN A C453 C471 C475 C478 C392 C410 C414 C417
External links
PDB RCSB:8yrs, PDBe:8yrs, PDBj:8yrs
PDBsum8yrs
PubMed
UniProtP46063|RECQ1_HUMAN ATP-dependent DNA helicase Q1 (Gene Name=RECQL)

[Back to BioLiP]