Structure of PDB 8yrh Chain A

Receptor sequence
>8yrhA (length=296) Species: 2697049 (Severe acute respiratory syndrome coronavirus 2) [Search protein sequence]
FRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNP
NYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVLKLKVDTANPKTPKYK
FVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLAGSCGSVGFNI
DYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITV
NVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGP
LSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVR
3D structure
PDB8yrh Structural basis of rosmarinic acid inhibitory mechanism on SARS-CoV-2 main protease.
ChainA
Resolution1.841 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ROA A T24 T25 C44 T45 S46 M49 C145 M165 E166 Q189 T22 T23 C42 T43 S44 M47 C143 M163 E164 Q187
External links
PDB RCSB:8yrh, PDBe:8yrh, PDBj:8yrh
PDBsum8yrh
PubMed38865813
UniProtP0DTD1|R1AB_SARS2 Replicase polyprotein 1ab (Gene Name=rep)

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