Structure of PDB 8yr4 Chain A

Receptor sequence
>8yr4A (length=586) Species: 9606 (Homo sapiens) [Search protein sequence]
DFGRKLRLLSGYLWPRGSPALQLVVLICLGLMGLERALNVLVPIFYRNIV
NLLTEKAPWNSLAWTVTSYVFLKFLQGGGTGSTGFVSNLRTFLWIRVQQF
TSRRVELLIFSHLHELSLRWHLGRRTGEVLRIADRGTSSVTGLLSYLVFN
VIPTLADIIIGIIYFSMFFNAWFGLIVFLCMSLYLTLTIVVTEWRTKFRR
AMNTQENATRARAVDSLLNFETVKYYNAESYEVERYREAIIKYQGLEWKS
SASLVLLNQTQNLVIGLGLLAGSLLCAYFVTEQKLQVGDYVLFGTYIIQL
YMPLNWFGTYYRMIQTNFIDMENMFDLLKEETEVKDLPGAGPLRFQKGRI
EFENVHFSYADGRETLQDVSFTVMPGQTLALVGPSGAGKSTILRLLFRFY
DISSGCIRIDGQDISQVTQASLRSHIGVVPQDTVLFNDTIADNIRYGRVT
AGNDEVEAAAQAAGIHDAIMAFPEGYRTQVGERGLKLSGGEKQRVAIART
ILKAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVN
ADQILVIKDGCIVERGRHEALLSRGGVYADMWQLQQ
3D structure
PDB8yr4 Cryo-EM structure of cadmium-bound human ABCB6.
ChainA
Resolution3.1 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FGA A N545 W546 N305 W306
External links
PDB RCSB:8yr4, PDBe:8yr4, PDBj:8yr4
PDBsum8yr4
PubMed38822018
UniProtQ9NP58|ABCB6_HUMAN ATP-binding cassette sub-family B member 6 (Gene Name=ABCB6)

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