Structure of PDB 8ypk Chain A

Receptor sequence
>8ypkA (length=201) Species: 10090 (Mus musculus) [Search protein sequence]
TIMAVQFNGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAAD
TQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIA
GWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDE
CLQFTANALALAMERDGSSGGVIRLAAIQESGVERQVLLGDQIPKFTIAT
L
3D structure
PDB8ypk Optimization of alpha-amido boronic acids via cryo-electron microscopy analysis: Discovery of a novel highly selective immunoproteasome subunit LMP7 ( beta 5i)/LMP2 ( beta 1i) dual inhibitor.
ChainA
Resolution2.7 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1L0C A T2 D17 T20 T21 T22 K33 R45 S46 G47 A49 G129 S130 S169 T1 D16 T19 T20 T21 K32 R44 S45 G46 A48 G128 S129 S168
External links
PDB RCSB:8ypk, PDBe:8ypk, PDBj:8ypk
PDBsum8ypk
PubMed38906067
UniProtQ60692|PSB6_MOUSE Proteasome subunit beta type-6 (Gene Name=Psmb6)

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