Structure of PDB 8yp3 Chain A

Receptor sequence

>8yp3A (length=471) Species: 7108 (Spodoptera frugiperda) [Search protein sequence]

YDSIFENLNSHGQGHLLKYWPDLSEKERAQLLNDLKKIDFAEVNELFRRA
NDTSKVIQEKVEDLKPIPDSHYEAVPNLSNEKILEYENIGLREISDGKVG
VLLLAGGQATRLGFGHPKGMYDVGLPSRKTLFQIQAERIVRVQQMAAEKY
GKEGKITWYIMTSEHTRGPTADYFRSHNYFGLNEEDIVYFEQGTLPCFDF
EGKIFLDEKYHVSSAPDGNGGLYRALKNQGVLDDIAKRGVEHLHAHSVDN
ILIKVADPVFIGYCKSKNADCAAKVVQKSTPSEAVGVVCRVNGHYKVVEY
SELTDEAAESRTADGRLTFSAGNICNHYFSSEFLTKICNFESKLKLHVAK
KKIPYVDHEGVRQKPTEPNGIKMEKFIFDVFEFAENFICLEVARDVEFSA
LKNNDAAKKDCPSTAREDLLRLHRKYVREAGGIVEDNIDVEISPLLSYGG
ENLTDLVSGEVFTISPYHLKS

3D structure

PDB

8yp3 Structure and Inhibition of Insect UDP- N -acetylglucosamine Pyrophosphorylase: A Key Enzyme in the Hexosamine Biosynthesis Pathway.

Chain

Resolution

2.12 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	UD1	A	L113 G115 G116 Q201 G227 N228 S256 V257 V294 G295 E308 Y309 N332 F387 K411	L104 G106 G107 Q192 G218 N219 S247 V248 V285 G286 E299 Y300 N323 F378 K402
BS02	MG	A	N332 C334 H336	N323 C325 H327

External links

PDB	RCSB:8yp3, PDBe:8yp3, PDBj:8yp3
PDBsum	8yp3
PubMed	39039661
UniProt	A0A2H1VI03

[Back to BioLiP]