Structure of PDB 8yon Chain A

Receptor sequence

>8yonA (length=441) Species: 2681598 (Escherichia phage T4) [Search protein sequence]

MQLNNRDLKSIIDNEALAYAMYTVENRAIPNMIDGFKPVQRFVIARALDL
ARGNKDKFHKLASIAGGVADLGYHHGENSAQDAGALMANTWNNNFPLLDG
QGNFGSRTVQKAAASRYIFARVSKNFYNVYKDTEYAPVHQDKEHIPPAFY
LPIIPTVLLNGVSGIATGYATYILPHSVSSVKKAVLQALQGKKVTKPKVE
FPEFRGEVVEIDGQYEIRGTYKFTSRTQMHITEIPYKYDRETYVSKILDP
LENKGFITWDDACGEHGFGFKVKFRKEYSLSDNEEERHAKIMKDFGLIER
RSQNITVINEKGKLQVYDNVVDLIKDFVEVRKTYVQKRIDNKIKETESAF
RLAFAKAHFIKKVISGEIVVQGKTRKELTEELSKIDMYSSYVDKLVGMNI
FHMTSDEAKKLAEEAKAKKEENEYWKTTDVVTEYTKDLEEI

3D structure

PDB

8yon structure of phage T6 full-length topoisomerase II bound with DNA

Chain

Resolution

6.73 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Y117 G168 R300 S302	Y117 G168 R300 S302
BS02	dna	A	R27 V39 G76 S79 A83 L86 I165 K246	R27 V39 G76 S79 A83 L86 I165 K246

External links

PDB	RCSB:8yon, PDBe:8yon, PDBj:8yon
PDBsum	8yon
PubMed
UniProt	P07065\|TOP5_BPT4 DNA topoisomerase medium subunit (Gene Name=52)

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