Structure of PDB 8yo4 Chain A

Receptor sequence

>8yo4A (length=442) Species: 2681598 (Escherichia phage T4) [Search protein sequence]

MQLNNRDLKSIIDNEALAYAMYTVENRAIPNMIDGFKPVQRFVIARALDL
ARGNKDKFHKLASIAGGVADLGYHHGENSAQDAGALMANTWNNNFPLLDG
QGNFGSRTVQKAAASRYIFARVSKNFYNVYKDTEYAPVHQDKEHIPPAFY
LPIIPTVLLNGVSGIATGYATYILPHSVSSVKKAVLQALQGKKVTKPKVE
FPEFRGEVVEIDGQYEIRGTYKFTSRTQMHITEIPYKYDRETYVSKILDP
LENKGFITWDDACGEHGFGFKVKFRKEYSLSDNEEERHAKIMKDFGLIER
RSQNITVINEKGKLQVYDNVVDLIKDFVEVRKTYVQKRIDNKIKETESAF
RLAFAKAHFIKKVISGEIVVQGKTRKELTEELSKIDMYSSYVDKLVGMNI
FHMTSDEAKKLAEEAKAKKEENEYWKTTDVVTEYTKDLEEIK

3D structure

PDB

8yo4 structure of phage T4 topoisomerase II central domain bound with DNA

Chain

Resolution

3.2 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	R116 Y117 I165 A166 G168 Q214 S302	R116 Y117 I165 A166 G168 Q214 S302
BS02	dna	A	R27 V39 Y73 H75 S163 I165	R27 V39 Y73 H75 S163 I165

External links

PDB	RCSB:8yo4, PDBe:8yo4, PDBj:8yo4
PDBsum	8yo4
PubMed
UniProt	P07065\|TOP5_BPT4 DNA topoisomerase medium subunit (Gene Name=52)

[Back to BioLiP]