Structure of PDB 8ym2 Chain A

Receptor sequence
>8ym2A (length=149) Species: 10090 (Mus musculus) [Search protein sequence]
TASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKEGTESTQDACAKMRAN
CQKSQMKKVPTIILSVSYKGVKFIDAANKNIIAEHEIRNISCAAQDPEDL
STFAYITKDSNHHYCHVFTAFDVNLAYEIILTLGQAFEVAYQLALQARK
3D structure
PDB8ym2 AIDA-1/ANKS1B binds to the SynGAP family GTPases with high affinity and specificity
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A T1035 A1036 S1037 T1038 I1125 I1128 S1129 C1130 A1131 A1132 Q1133 I1170 L1171 F1177 A1180 Y1181 T1 A2 S3 T4 I87 I90 S91 C92 A93 A94 Q95 I130 L131 F137 A140 Y141
External links
PDB RCSB:8ym2, PDBe:8ym2, PDBj:8ym2
PDBsum8ym2
PubMed38759928
UniProtQ8BIZ1|ANS1B_MOUSE Ankyrin repeat and sterile alpha motif domain-containing protein 1B (Gene Name=Anks1b)

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