Structure of PDB 8yl9 Chain A

Receptor sequence
>8yl9A (length=346) Species: 104259 (Penicillium brasilianum) [Search protein sequence]
DFLSGAFHYSDSVNPSKYSPRPSDYFGTLPFRTSRFEREAADVTADYLRK
WQKAVKADNPERLVFHGSTTTLGHFVSWAYPECIPDRVDLCTQICDFGFY
WDDVTDSVNVQENAEITQDLALALLSELTGQRLEPKLEINKIVVQMLWGV
LDKDRKSGLEMIKFWKGHLDGQAEHNNMSFEEYTKHRLSEVGARWAVEVG
CWSLGINLSREKKDSVAHFVNKGLLAAALMNDYYSFNKEFDEHQRAGSMD
RLQNGLGILMREYGYTETEARSILREEIRKGERAIMDGYIAWRESADSSS
ESHELNRYIVMIILMIGGITFWSSHASRYHRDDLITTAGDRAMIVG
3D structure
PDB8yl9 Structural Insights into the Terpene Cyclization Domains of Two Fungal Sesterterpene Synthases and Enzymatic Engineering for Sesterterpene Diversification.
ChainA
Resolution2.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.29: geranylgeranyl diphosphate synthase.
2.5.1.81: geranylfarnesyl diphosphate synthase.
4.2.3.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D105 D109 D102 D106
BS02 MG A D105 D109 D102 D106
BS03 MG A N237 S241 E245 N231 S235 E239
BS04 PPV A D105 R193 N237 S241 E245 R334 Y335 D102 R187 N231 S235 E239 R328 Y329
BS05 BTM A G101 F102 D105 V197 R334 G98 F99 D102 V191 R328
External links
PDB RCSB:8yl9, PDBe:8yl9, PDBj:8yl9
PDBsum8yl9
PubMed38584136
UniProtA0A2Z6AQX7|PBSS_PENBI Sesterbrasiliatriene synthase PbSS (Gene Name=PbSS)

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