Structure of PDB 8y6k Chain A

Receptor sequence
>8y6kA (length=741) Species: 9606 (Homo sapiens) [Search protein sequence]
NPAHAHFESFLQAQLCQDVLSSFQELCGALGLEPGGGLPQYHKIKDQLNY
WSAKSLWTKLDKRAGQPVYQQGRACTSTKCLVVGAGPCGLRVAVELALLG
ARVVLVEKRTKFSRHNVLHLWPFTIHDLRALGAKKFYGRFCTGTLDHISI
RQLQLLLLKVALLLGVEIHWGVTFTGLQPPPRKGSGWRAQLQPNPPAQLA
NYEFDVLISAAGGKFVPEGFKVREMRGKLAIGITANFVNGRTVEETQVPE
ISGVARIYNQSFFQSLLKATGIDLENIVYYKDDTHYFVMTAKKQCLLRLG
VLRQDWPDTNRLLGSANVVPEALQRFTRAAADFATHGKLGKLEFAQDAHG
QPDVSAFDFTSMMRAESSARVQEKHGARLLLGLVGDCLVEPFWPLGTGVA
RGFLAAFDAAWMVKRWAEGAESLEVLAERESLYQLLSQTSPENMHRNVAQ
YGLDPATRYPNLNLRAVTPNQVRDLYDVLGTQEELLRWCQEQTAGYPGVH
VSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALEATAWALKVAENE
LGITPVVSAQAVVAGSDPLGLIAYLSHFHSAFKSMAHGDLCALCGEHLYV
LERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHFYCLQHLPLRRA
KEEEMKRFCKAQTIQRRLNEIEAALRELEAEGVKLELALRRQSSSPEQQK
KLWVGQLLQLVDKKNSLVAEEAELMITVQELNLEEKQWQLD
3D structure
PDB8y6k Autoinhibition and relief mechanisms for MICAL monooxygenases in F-actin disassembly.
ChainA
Resolution3.94 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C697 F717 H718 C591 F611 H612
BS02 ZN A C724 H750 C618 H644
BS03 FAD A A92 G93 P94 C95 E114 K115 N123 V124 L125 V179 F181 A218 Y293 D393 W400 V406 A85 G86 P87 C88 E107 K108 N116 V117 L118 V172 F174 A211 Y286 D386 W393 V399
External links
PDB RCSB:8y6k, PDBe:8y6k, PDBj:8y6k
PDBsum8y6k
PubMed39122694
UniProtQ8TDZ2|MICA1_HUMAN [F-actin]-monooxygenase MICAL1 (Gene Name=MICAL1)

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