Structure of PDB 8y2d Chain A

Receptor sequence
>8y2dA (length=528) Species: 9606 (Homo sapiens) [Search protein sequence]
DFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYLLFMVIAGMPLFYME
LALGQFNREGAAGVWKICPILKGVGFTVILISLYVGFFYNVIIAWALHYL
FSSFTTELPWIHCNNSWNSPNCSDGTTPAAEYFERGVLHLHQSHGIDDLG
PPRWQLTACLVLVIVLLYFSLWKVWITATMPYVVLTALLLRGVTLPGAID
GIRAYLSVDFYRLCEASVWIDAATQVCFSLGVGFGVLIAFSSYNKFTNNC
YRDAIVTTSINSLTSFSSGFVVFSFLGYMAQKHSVPIGDVAKDGPGLIFI
IYPEAIATLPLSSAWAVVFFIMLLTLGIDSAMGGMESVITGLIDEFQLLH
RHRELFTLFIVLATFLLSLFCVTNGGIYVFTLLDHFAAGTSILFGVLIEA
IGVAWFYGVGQFSDDIQQMTGQRPSLYWRLCWKLVSPCFLLFVVVVSIVT
FRPPHYGAYIFPDWANALGWVIATSSMAMVPIYAAYKFCSLPGSFREKLA
YAIAPEKDRELVDRGEVRQFTLRHWLKV
3D structure
PDB8y2d Dopamine reuptake and inhibitory mechanisms in human dopamine transporter
ChainA
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LDP A D79 S149 V152 G153 S422 D12 S82 V85 G86 S330
External links
PDB RCSB:8y2d, PDBe:8y2d, PDBj:8y2d
PDBsum8y2d
PubMed39112701
UniProtQ01959|SC6A3_HUMAN Sodium-dependent dopamine transporter (Gene Name=SLC6A3)

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