Structure of PDB 8xyb Chain A

Receptor sequence
>8xybA (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
QGQWQRRRRLDGALNRVPVGFYQKVWKVLQKCHGLSVEGFVLPSSTTREM
TPGEIKFSVHVESVLNRVPQPEYRQLLVEAILVLTMLADIEIHSIGSIIA
VEKIVHIANDLFLQEQKTLGADDTMLAKDPASGICTLLYDSAPSGRFGTM
TYLSKAAATYVQEFLPHSICAMQ
3D structure
PDB8xyb Architecture and activation of human muscle phosphorylase kinase
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAR A K1081 L1137 A1138 E1141 V1211 C1220 K31 L87 A88 E91 V161 C170
Gene Ontology
Molecular Function
GO:0004689 phosphorylase kinase activity
GO:0005516 calmodulin binding
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0005977 glycogen metabolic process
GO:0006091 generation of precursor metabolites and energy
GO:0045819 positive regulation of glycogen catabolic process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005964 phosphorylase kinase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8xyb, PDBe:8xyb, PDBj:8xyb
PDBsum8xyb
PubMed38548794
UniProtP46020|KPB1_HUMAN Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (Gene Name=PHKA1)

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