Structure of PDB 8xtg Chain A

Receptor sequence
>8xtgA (length=394) Species: 5074 (Penicillium brevicompactum) [Search protein sequence]
SPASIIQELASAAKQYENNESGAREALIAQSRALIASLEVPSEFIQHTFW
SQPALSAIVRLATDVNLFQYLKDAQEEGLNAEALASKTGMDVSLFARLAR
HLVAMNVITSRNGVFYGTALSNGLAAENYQQSIRFCHDVSRPSFGAFPSF
FKGNGYKTPALGTTDGPFQSAHKVDISFPQWLVGNPPYLQYFNSYMSAYR
AGKPNWCDNGFYPVADRLLNGFDASVSDVLLVDVGGGRGHDIATFGSQFS
PLPGRLVLQDREQVINSIPADESRQFEATTHDIFTTQPVKHARAYYMHSV
PHGFGDEDAVKIMANLVPALAKGYSRVLLNEIVVDEERPVMSATNMDLIM
LAHMGAKERTEADWRSILTRAGLKVVNIYSYPGVAESLIEAELA
3D structure
PDB8xtg Structural basis for substrate flexibility of the O-methyltransferase MpaG' involved in mycophenolic acid biosynthesis.
ChainA
Resolution2.0 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAH A M200 Y203 G239 D264 R265 H285 D286 I287 H302 S303 M196 Y199 G235 D260 R261 H281 D282 I283 H298 S299
BS02 A1LWD A Y199 M200 Y203 R265 H306 I353 M354 H357 Y195 M196 Y199 R261 H302 I349 M350 H353
External links
PDB RCSB:8xtg, PDBe:8xtg, PDBj:8xtg
PDBsum8xtg
PubMed39150221
UniProtA0A0B5L781|MPAG2_PENBR O-methyltransferase mpaG' (Gene Name=mpaG')

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