Structure of PDB 8xox Chain A

Receptor sequence
>8xoxA (length=261) Species: 9606 (Homo sapiens) [Search protein sequence]
QYGIAREDVVLNRILGEGFFGEVYEGVYTNHKGEKINVAVKTCKKDCTLD
NKEKFMSEAVIMKNLDHPHIVKLIGIIEEEPTWIIMELYPYGELGHYLER
NKNSLKVLTLVLYSLQICKAMAYLESINCVHRDIAVRNILVASPECVKLG
DFGLSLPIKWMSPESINFRRFTTASDVWMFAVCMWEILSFGKQPFFWLEN
KDVIGVLEKGDRLPKPDLCPPVLYTLMTRCWDYDPSDRPRFTELVCSLSD
VYQMEKDIAME
3D structure
PDB8xox The Crystal Structure of FAK2 from Biortus.
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 YAM A L431 G432 E433 V439 M502 E503 Y505 G508 E509 L15 G16 E17 V23 M86 E87 Y89 G92 E93
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8xox, PDBe:8xox, PDBj:8xox
PDBsum8xox
PubMed
UniProtQ14289|FAK2_HUMAN Protein-tyrosine kinase 2-beta (Gene Name=PTK2B)

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