Structure of PDB 8xoa Chain A

Receptor sequence
>8xoaA (length=376) Species: 9606 (Homo sapiens) [Search protein sequence]
SRKLILFIVFLALLLDNMLLTVVVPIIPSYLYVGLLFASKATVQLITNPF
IGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSYAFLLIARSLQGIGSSC
SSVAGMGMLASVYTDDEERGNVMGIALGGLAMGVLVGPPFGSVLYEFVGK
TAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKGTPLTTLLKDPYILIAA
GSICFANMGIAMLEPALPIWMMETMCSRKWQLGVAFLPASISYLIGTNIF
GILAHKMGRWLCALLGMIIVGVSILCIPFAKNIYGLIAPNFGVGFAIGMV
DSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMGYAIGPSAGGAIAKAIG
FPWLMTIIGIIDILFAPLCFFLRSPP
3D structure
PDB8xoa VMAT2 complex with MPP+
ChainA
Resolution3.03 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WRF A F334 Y341 F429 Y433 F236 Y243 F331 Y335
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:8xoa, PDBe:8xoa, PDBj:8xoa
PDBsum8xoa
PubMed
UniProtQ05940|VMAT2_HUMAN Synaptic vesicular amine transporter (Gene Name=SLC18A2)

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