Structure of PDB 8xo9 Chain A

Receptor sequence
>8xo9A (length=392) Species: 9606 (Homo sapiens) [Search protein sequence]
RSRKLILFIVFLALLLDNMLLTVVVPIIPSYLYSIKHEDKDLLNENVQVG
LLFASKATVQLITNPFIGLLTNRIGYPIPIFAGFCIMFVSTIMFAFSSSY
AFLLIARSLQGIGSSCSSVAGMGMLASVYTDAEEAGNVMGIALGGLAMGV
LVGPPFGSVLYEFVGKTAPFLVLAALVLLDGAIQLFVLQPSRVQPESQKG
TPLTTLLKDPYILIAAGSICFANMGIAMLEPALPIWMMETMCSRKWQLGV
AFLPASISYLIGTNIFGILAHKMGRWLCALLGMIIVGVSILCIPFAKNIY
GLIAPNFGVGFAIGMVDSSMMPIMGYLVDLRHVSVYGSVYAIADVAFCMG
YAIGPSAGGAIAKAIGFPWLMTIIGIIDILFAPLCFFLRSPP
3D structure
PDB8xo9 VMAT2 complex with noradrenaline in cytosol-facing state
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 E5E A V232 I308 Y341 Y433 V150 I226 Y259 Y351
Gene Ontology
Molecular Function
GO:0022857 transmembrane transporter activity
Biological Process
GO:0055085 transmembrane transport

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Molecular Function
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Biological Process
External links
PDB RCSB:8xo9, PDBe:8xo9, PDBj:8xo9
PDBsum8xo9
PubMed
UniProtQ05940|VMAT2_HUMAN Synaptic vesicular amine transporter (Gene Name=SLC18A2)

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