Structure of PDB 8xn8 Chain A

Receptor sequence
>8xn8A (length=450) Species: 10090 (Mus musculus) [Search protein sequence]
VTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYI
PSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKG
AYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSK
HADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVW
MGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEE
PIYIVTEYMNKGSLLDFLKGETGKYLRLPQLVDMSAQIASGMAYVERMNY
VHRDLRAANILVGENLVCKVADFGLARLIEDNEYTARQGAKFPIKWTAPE
AALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMP
CPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGEN
3D structure
PDB8xn8 The Crystal Structure of SRC from Biortus.
ChainA
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A L275 G278 V283 A295 K297 M343 R390 N393 L395 L191 G194 V199 A211 K213 M259 R306 N309 L311
BS02 MG A N393 D406 N309 D322
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:8xn8, PDBe:8xn8, PDBj:8xn8
PDBsum8xn8
PubMed
UniProtP05480|SRC_MOUSE Proto-oncogene tyrosine-protein kinase Src (Gene Name=Src)

[Back to BioLiP]