Structure of PDB 8x2a Chain A

Receptor sequence
>8x2aA (length=259) Species: 9606 (Homo sapiens) [Search protein sequence]
GELKREEITLLKELGSGQFGVVQLGKWKGQYDVAVKMIKEGSMSEDEFFQ
EAQTMMKLSHPKLVKFYGVCSKEYPIYIVTEYISNGCLLNYLRSHGKGLE
PSQLLEMCYDVCEGMAFLESHQFIHRDLAARNCLVDRDLCVKVSDFGMTR
YVLDDQYVGTKFPVKWSAPEVFHYFKYSSKSDVWAFGILMWEVFSLGKQP
YDLYDNSQVVLKVSQGHRLYRPHLASDTIYQIMYSCWHELPEKRPTFQQL
LSSIEPLRE
3D structure
PDB8x2a The Crystal Structure of BMX from Biortus.
ChainA
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 LTJ A G424 V431 A443 Y491 I492 G495 C496 N499 L543 G15 V22 A34 Y82 I83 G86 C87 N90 L134
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8x2a, PDBe:8x2a, PDBj:8x2a
PDBsum8x2a
PubMed
UniProtP51813|BMX_HUMAN Cytoplasmic tyrosine-protein kinase BMX (Gene Name=BMX)

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