Structure of PDB 8wxw Chain A

Receptor sequence
>8wxwA (length=1078) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence]
MEWIHEKSPKHNSYDIIEKRYNEEFKMTYTVYQHKKAKTQVISLGTNDPL
DVEQAFAFYVKTLTHSGKGIPHILQHSVLSGSKNYNYKNSIGLLEKGTLH
THLNAYTFNDRTVYMAGSMNNKDFFNIMGVYMDSVFQPNVLENKYIFETE
GWTYEVEKLKEDEKGKAEIPQMKDYKVSFNGIVYNEMKGALSSPLEDLYH
EEMKYMFPDNVHSNNSGGDPKEITNLTYEEFKEFYYKNYNPKKVKVFFFS
KNNPTELLNFVDQYLGQLDYSKYRDDAVESVEYQTYKKGPFYIKKKYGDH
SEEKENLVSVAWLLNPKVSDLSLENPTDYFVLLIINNLLIHTPESVLYKA
LTDCGLGNNVIDRGLNDSLVQYIFSIGLKGIKRNNEKIKNFDKVHYEVED
VIMNALKKVVKEGFNKSAVEASINNIEFILKEANLKTSKSIDFVFEMTSK
LNYNRDPLLIFEFEKYLNIVKNKIKNEPMYLEKFVEKHFINNAHRSVILL
EGDENYAQEQENLEKQELKKRIENFNEQEKEQVIKNFEELSKYKNAEESP
EHLNKFPIISISDLNKKTLEVPVNVYFTNINENNNIMETYNKLKTNEHML
KDNMDVFLKKYVLKNTKYEGNVPILVYEMPTTGIVYLQFVFSLDHLTVDE
LAYLNLFKTLILENKTNKRSSEDFVILREKNIGSMSANVALYSKDDHLNV
TDKYNAQALFNLEMHVLSHKCNDALNIALEAVKESDFSNKKKVIDILKRK
INGMKTTFSEKGYAILMKYVKAHLNSKHYAHNIIYGYENYLKLQEQLELA
ENDFKTLENILVRIRNKIFNKKNLMVSVTSDYGALKHLFVNSNESLKNLV
SYFEENDKYINVMGWNEEIKSKKLFDEEKVKKEFFVLPTFVNSVSMSGIL
FKPGEYLDPSFTVIVAALKNSYLWDTVRGLNGAYGVFADIEYDGSVVFLS
ARDPNLEKTLATFRESAKGLRKMADTMTENDLLRYIINTIGTIDKPRRGI
ELSKLSFLRLISNESEQDRVEFRKRIMNTKKEDFYKFADLLESKVNEFEK
NIVIITTKEKANEYIANVDGEFKKVLIE
3D structure
PDB8wxw Falcilysin in complex with hemoglobin alpha chain peptide
ChainA
Resolution1.86 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q132 H133 I148 E152 N161 A162 Y163 T164 G274 R1043 Y1049 Q75 H76 I91 E95 N104 A105 Y106 T107 G217 R928 Y934
BS02 ZN A H129 H133 E243 H72 H76 E186
External links
PDB RCSB:8wxw, PDBe:8wxw, PDBj:8wxw
PDBsum8wxw
PubMed
UniProtQ76NL8|FCLN_PLAF7 Falcilysin (Gene Name=FLN)

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