Structure of PDB 8wp1 Chain A

Receptor sequence
>8wp1A (length=304) Species: 9606 (Homo sapiens) [Search protein sequence]
ATCKNWLAAEAALEKYYLSIFYGIEFVVGVLGNTIVVYGYIFSLKNWNSS
NIYLFNLSVSDLAFLCTLPMLIRSYANGNWIYGDVLCISNRYVLHANLYT
SILFLTFISIDRYLIIKYPFREHLLQKKEFAILISLAIWVLVTLELLPIL
PLINPVITDNGTTCNDFASSGDPNYNLIYSMCLTLLGFLIPLFVMCFFYY
KIALFLKQRNRQVATALPLEKPLNLVIMAVVIFSVLFTPYHVMRNVRIAS
RLGSWKQYQCTQVVINSFYIVTRPLAFLNSVINPVFYFLLGDHFRDMLMN
QLRH
3D structure
PDB8wp1 Structural insights into ligand recognition and activation of the succinate receptor SUCNR1.
ChainA
Resolution3.15 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 U9S A Y83 R99 L102 D174 R281 Y75 R91 L94 D166 R273
External links
PDB RCSB:8wp1, PDBe:8wp1, PDBj:8wp1
PDBsum8wp1
PubMed38923454
UniProtQ9BXA5|SUCR1_HUMAN Succinate receptor 1 (Gene Name=SUCNR1)

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