Structure of PDB 8wp0 Chain A

Receptor sequence
>8wp0A (length=1217) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]
EQSLPFFKLFSFADKFDYLLMFVGSLGAIVHGSSMPVFFLLFGQMVNGFG
KNQMDLHQMVHEVSRYSLYFVYLGLVVCFSSYAEIACWMYSGERQVAALR
KKYLEAVLKQDVGFFDTDARTGDIVFSVSTDTLLVQDAISEKVGNFIHYL
STFLAGLVVGFVSAWKLALLSVAVIPGIAFAGGLYAYTLTGITSKSRESY
ANAGVIAEQAIAQVRTVYSYVGESKALNAYSDAIQYTLKLGYKAGMAKGL
GLGCTYGIACMSWALVFWYAGVFIRNGQTDGGKAFTAIFSAIVGGMSLGQ
SFSNLGAFSKGKAAGYKLMEIINQRPTIIQDPLDGKCLDQVHGNIEFKDV
TFSYPSRPDVMIFRNFNIFFPSGKTVAVVGGSGSGKSTVVSLIERFYDPN
SGQILLDGVEIKTLQLKFLREQIGLVNQEPALFATTILENILYGKPDATM
VEVEAAASAANAHSFITLLPKGYDTQVGERGVQLSGGQKQRIAIARAMLK
DPKILLLDQATSALDASSESIVQEALDRVMVGRTTVVVAHRLCTIRNVDS
IAVIQQGQVVETGTHEELIAKSGAYASLIRFQEMVSTRLSHSLSTKSLSL
RSGSLRNLSYSYSTGADGRIEMISNAETDRKTRAPENYFYRLLKLNSPEW
PYSIMGAVGSILSGFIGPTFAIVMSNMIEVFYYTDYDSMERKTKEYVFIY
IGAGLYAVGAYLIQHYFFSIMGENLTTRVRRMMLSAILRNEVGWFDEDEH
NSSLIAARLATDAADVKSAIAERISVILQNMTSLLTSFIVAFIVEWRVSL
LILGTFPLLVLANFAQQLSLKGFAGDTAKAHAKTSMIAGEGVSNIRTVAA
FNAQSKILSLFCHELRVPQKRSLYRSQTSGFLFGLSQLALYGSEALILWY
GAHLVSKGVSTFSKVIKVFVVLVITANSVAETVSLAPEIIRGGEAVGSVF
SVLDRQTRIDPDDADADPVETIRGDIEFRHVDFAYPSRPDVMVFRDFNLR
IRAGHSQALVGASGSGKSSVIAMIERFYDPLAGKVMIDGKDIRRLNLKSL
RLKIGLVQQEPALFAATIFDNIAYGKDGATESEVIDAARAANAHGFISGL
PEGYKTPVGERGVQLSGGQKQRIAIARAVLKNPTVLLLDQATSALDAESE
CVLQEALERLMRGRTTVVVAHRLSTIRGVDCIGVIQDGRIVEQGSHSELV
SRPEGAYSRLLQLQTHR
3D structure
PDB8wp0 Structure and function of the ABC transporter ABCB19 in brassinosteroid export
ChainA
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP A G405 K406 S407 Q529 G385 K386 S387 Q509
BS02 ATP A Y1019 R1022 G1050 K1051 S1052 T1176 Y985 R988 G1016 K1017 S1018 T1142
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0010329 auxin efflux transmembrane transporter activity
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0008361 regulation of cell size
GO:0009637 response to blue light
GO:0009639 response to red or far red light
GO:0009640 photomorphogenesis
GO:0009733 response to auxin
GO:0009734 auxin-activated signaling pathway
GO:0009926 auxin polar transport
GO:0009958 positive gravitropism
GO:0010218 response to far red light
GO:0010315 auxin export across the plasma membrane
GO:0010540 basipetal auxin transport
GO:0010541 acropetal auxin transport
GO:0043481 anthocyanin accumulation in tissues in response to UV light
GO:0048364 root development
GO:0048443 stamen development
GO:0048527 lateral root development
GO:0055085 transmembrane transport
GO:0060918 auxin transport
GO:0090691 formation of plant organ boundary
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8wp0, PDBe:8wp0, PDBj:8wp0
PDBsum8wp0
PubMed38513023
UniProtQ9LJX0|AB19B_ARATH ABC transporter B family member 19 (Gene Name=ABCB19)

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