Structure of PDB 8woz Chain A

Receptor sequence
>8wozA (length=596) Species: 9986 (Oryctolagus cuniculus) [Search protein sequence]
STIEELAKTFLEKFNQEAEDLSYQSALASWDYNTNITEENVQKMNDAEAK
WSAFYEEQSKLAKTYPSQEVQNLTVKRQLQALQQSGSSALSADKSKQLNT
ILSTMSTIYSTGKVCNQSNPQECFLLEPGLDEIMAKSTDYNERLWAWEGW
RSVVGKQLRPLYEEYVVLKNEMARANNYEDYGDYWRADYEAEGADGYDYS
RSQLIDDVERTFSEIKPLYEQLHAFVRTKLMDAYPSRISPTGCLPAHLLG
DMWGRFWTNLYSLTVPFGQKPNIDVTDTMVNQGWDAERIFKEAEKFFVSV
GLPSMTQGFWENSMLTEPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMDN
FLTAHHEMGHIQYDMAYATQPFLLRNGANEGFHEAVGEIMSLSAATPEHL
KSIGLLPYDFHEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEI
PKEQWMQKWWEMKREIVGVVEPMPHDETYCDPAALFHVANDYSFIRYYTR
TIYQFQFQEALCQAAQHEGPLHKCDISNSTEAGQKLLNMLRLGRSEPWTL
ALENVVGAKNMDVRPLLNYFEPLFTWLKEQNRNSFVGWSTEWTPYA
3D structure
PDB8woz Structural basis of increased binding affinities of spikes from SARS-CoV-2 Omicron variants to rabbit-hare ACE2s reveals the expanding host tendency
ChainA
Resolution3.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
3.4.17.23: angiotensin-converting enzyme 2.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A H374 H378 H356 H360
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0008241 peptidyl-dipeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8woz, PDBe:8woz, PDBj:8woz
PDBsum8woz
PubMed38112468
UniProtG1TEF4

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