Structure of PDB 8wo8 Chain A

Receptor sequence
>8wo8A (length=463) Species: 186497 (Pyrococcus furiosus DSM 3638) [Search protein sequence]
SEIAVRIRGIYSTALTKLLMDRGFKIVQPSDVIAERFGIEKSYEDFDVDI
YDKNHGVTIVGTKVEAVKKVFEEEFIDVFFRKLPYKLHGIYKGLVVKRDD
RFVYVDIGNVIGTVLIEELPDAAEGDEVVVQVKKHNVLPHLSTLITIPGD
YAVLIPKPVQRHVKISRKIKDPEERERLRILGLSVDLGEWGVLWRTAAAY
KDWNTLRDELVRLSKIADKLKEAEKFSAPAEIIEGREIYEIEFGGGVKKK
LDEIRNEVVPTIEGHHQFKSYDPEFTLAVDVAEGILAKLPSQRQKISKGF
LEAIITSKGPKVGWIFTLNHVKPDGQIIKIGPGEVIEVSTDPLKVTIKRY
LRPGKFYDGLEVPIESGDYAITEIEAGKWWFVHRYYDKDGNLKGEFYNIN
TPVEIYPDKARYVDLEVDIVRWPDGKKEIIDKEKLKEHYEEGIISEKLYK
ATLRIAQEVYDRL
3D structure
PDB8wo8 Homo-trimeric structure of the ribonuclease for rRNA processing, FAU-1, from Pyrococcus furiosus.
ChainA
Resolution2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A R10 H92 P152 K170 S172 R173 K174 L199 R201 T202 R6 H88 P148 K164 S166 R167 K168 L193 R195 T196
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0016891 RNA endonuclease activity, producing 5'-phosphomonoesters
GO:0035925 mRNA 3'-UTR AU-rich region binding
Biological Process
GO:0006364 rRNA processing

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Molecular Function
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Biological Process
External links
PDB RCSB:8wo8, PDBe:8wo8, PDBj:8wo8
PDBsum8wo8
PubMed38302756
UniProtQ8U4Q7|FAU1_PYRFU Probable ribonuclease FAU-1 (Gene Name=fau-1)

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