Structure of PDB 8wil Chain A

Receptor sequence
>8wilA (length=574) Species: 1491393 (Jingmen tick virus) [Search protein sequence]
ERITPEWTAEAVIEGCAPLTPLNMTRSIAEMHMEYPPLGITRFFKELGYK
IAKKKRKNRFVGQLIEPLRRVLERHHLFGATSTTPRAVFNMFRSKVDRAP
VELHSHYPGLKKMYDILADLWLERYGSMKRLTEEEMASAINRRGAMGYQM
DNRNYGDLGAYWDSGDWRQDVNTFKRALLSGTPTHAVYNTTAKRIIQYLP
ADARLYELKVLGGLHKYLEKCGWSVAGQGLYKYGDRVKKSMDATGAAISE
DVAGWDTKISKGLLTLESHMFTKLAEDEEMAREIHHLYRLYADPHMVVQR
EIEGEVHDVLLRGRGQVSSGRQPTYAANTITNFITTTYGMAVTLGIPEAD
WPRLIRDLTDERGNRRLLVSGDDKVLFLRGDEARVYASSAYRISNDMGLV
RKDMALEQESEIIVDVKEISFCSHRYWPVKYGNEIHYMPVRDVGEIFAKA
TMADMTQEAWARVQGLNMLVNYHHIPECRMLALAILSVTRIGLNLKGIST
EWLRDDLAPDTIHALITEGRTSGWDQLGYVDFKDRKGILLRPDTNYKNWR
RDLPEKVRQLREDGQYKDWLQKMA
3D structure
PDB8wil A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG A D698 K699 D373 K374
Gene Ontology
Molecular Function
GO:0003724 RNA helicase activity
GO:0003968 RNA-dependent RNA polymerase activity
GO:0005524 ATP binding
GO:0008168 methyltransferase activity
GO:0016787 hydrolase activity
GO:0017111 ribonucleoside triphosphate phosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0001172 RNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0032259 methylation
GO:0039694 viral RNA genome replication
Cellular Component
GO:0016020 membrane
GO:0042025 host cell nucleus

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8wil, PDBe:8wil, PDBj:8wil
PDBsum8wil
PubMed38296832
UniProtA0A7D0QVD8

[Back to BioLiP]