Structure of PDB 8wgf Chain A

Receptor sequence
>8wgfA (length=345) Species: 9606 (Homo sapiens) [Search protein sequence]
VDNQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIK
KLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVY
LVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPS
NIVVKSDCTLKILDFGLARSFMMTPYVVTRYYRAPEVILGMGYKENVDIW
SVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNY
VENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKR
ISVDDALQHPYINVWYDPAEVEAPPDEREHTIEEWKELIYKEVMN
3D structure
PDB8wgf The Crystal Structure of JNK3 from Biortus.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.24: mitogen-activated protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ANP A I32 S34 G35 Q37 V40 A53 K55 R69 M108 M111 N114 S155 L168 I27 S29 G30 Q32 V35 A48 K50 R64 M103 M106 N109 S150 L163
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0004707 MAP kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:8wgf, PDBe:8wgf, PDBj:8wgf
PDBsum8wgf
PubMed
UniProtP53779|MK10_HUMAN Mitogen-activated protein kinase 10 (Gene Name=MAPK10)

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