Structure of PDB 8wg3 Chain A

Receptor sequence
>8wg3A (length=548) Species: 6100,10090 [Search protein sequence]
DYCYSARIRSTVLQGLPFGGVPTVLALDFMCFLALLFLFSILRKVAWNGF
CSWLTAIFRIKDDEIRDKCGGDAVHYLSFQRHIIGLLVVVGVLSVGIVLP
VNFSGDLLENNAYSFGRTTIANLKSGNNLLWLHTSFAFLYLLLTVYSMRR
HTSKMRVKRTLFINGISKYAESEKIKKHFEEAYPNCTVLEARPCYKPLGM
AFVTFHNETITAIILKDFNVCKCQGCTCRGEPRASSCSEALHISNWTVTY
APDPQNIYWEHLSIRGFIWWLRCLVINVVLFILLFFLTTPAIIITTMDKF
NVTKPVEYLNNPIITQFFPTLLLWCFSALLPTIVYYSAFFEAHWTRSGEN
RTTMHKCYTFLIFMVLLLPSLGLSSLDLFFRWLFDECVFLPDNGAFFVNY
VIASAFIGNAMDLLRIPGLLMYEFQFGAAYAWMMCVFTVVMTYSITCPII
VPFGLMYMLLKHLVDRYNLYYAYLPAKLDKKIHSGAVNQVVAAPILCLFW
LLFFSTMRTGFLAPTSMFTFVVLVITIVICLCHVCFGHFKYLSAHNYK
3D structure
PDB8wg3 Mechanosensitive channel TMEM63B functions as a plasma membrane lipid scramblase
ChainA
Resolution3.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 Y01 A R512 H516 F524 L690 F693 R351 H355 F363 L496 F499
BS02 Y01 A N682 I721 N488 I527
BS03 Y01 A F442 R512 T520 F281 R351 T359
BS04 LBN A W430 N438 H504 W505 W269 N277 H343 W344
External links
PDB RCSB:8wg3, PDBe:8wg3, PDBj:8wg3
PDBsum8wg3
PubMed
UniProtP42212|GFP_AEQVI Green fluorescent protein (Gene Name=GFP);
Q3TWI9

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