Structure of PDB 8wco Chain A

Receptor sequence
>8wcoA (length=275) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MNRQIVRSALFVPATRPERIPKALASGADRVIVDLEDAVEEGLKVEARAN
LRRFLVDTPEARVLVRINAAEHPGHADDLALCRDHAGVIGLLLPKVESAA
QVRHAAVASGKPVWPIVESARGLAALGEIAAAAGVERLSFGSLDLALDLD
LNSGSNAAEQILGHARYALLLQTRLAGLAPPLDGVYPAIQNRAGLVEAVR
FARDMGFGGLLCIHPSQVEPIHQTLMPSPAELEWARRVAEAGASGAGVFV
VDGEMVDAPVLGRARRLLERAGEGG
3D structure
PDB8wco Structural and functional characterization of itaconyl-CoA hydratase and citramalyl-CoA lyase involved in itaconate metabolism of Pseudomonas aeruginosa.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ACO A F11 V12 R19 K22 A23 R66 I213 H214 P215 F11 V12 R19 K22 A23 R66 I213 H214 P215
BS02 ACO A M255 D257 M255 D257
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0003824 catalytic activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006107 oxaloacetate metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8wco, PDBe:8wco, PDBj:8wco
PDBsum8wco
PubMed38677288
UniProtQ9I562

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