Structure of PDB 8w8j Chain A

Receptor sequence
>8w8jA (length=572) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
HHMRTSQYLLSTLKETPADAVVISHQLLLRAGMIRRLASGLYTWLPMGLR
VLRKVETIVREEMNAAGALEVLMPAVQPAELWQESGRWEQYGPELLRLKD
RHEREFCVGPTHEEVITDLARNELNSYKQLPINFYQIQTKFRDEIRPRFG
LMRGREFIMKDAYSFHLSQDSLQQTYDGMYQAYSKIFSRLGLDFRPVQAD
NGSIGGSGSHEFHVLANSGEDDIVFSDSSDYAANIEKAEAVPRESARGSA
TEDMRLVDTPNTKTIAALVDGFQLPIEKTIKTLVVHGAEEGTLVALIVRG
DHELNEIKAANQPLVASPLVFASEAEIRAAIGAGPGSLGPVNLPIACIVD
RSVALMSDFAAGANIEDKHYFGVNWERDLPLPEVADLRNVVEGDPSPDGK
GTLVIKRGIEVGHIFQLGTKYSEAMKLSVLSEQGKPVNLIMGCYGIGVSR
VVAAAIEQNHDERGILWPSALAPFQIALVPLKYETESVKQATDKLYAELT
AAGFEVLLDDRDKKTSPGVKFADMELIGIPHRIVISDRGLSEGVLEYKGR
RDSESQNLPIGELMSFITEKLS
3D structure
PDB8w8j Structure-Guided Fluorine Scanning Accelerates the Discovery of Potent and Selective Inhibitors Against Bacterial Prolyl-tRNA Synthetase
ChainA
Resolution1.807 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 W1Q A T109 E111 R140 M150 G152 F155 M157 D159 Y161 H411 F413 C441 Y442 G443 G445 R448 T111 E113 R142 M152 G154 F157 M159 D161 Y163 H413 F415 C443 Y444 G445 G447 R450
External links
PDB RCSB:8w8j, PDBe:8w8j, PDBj:8w8j
PDBsum8w8j
PubMed
UniProtQ9I502|SYP_PSEAE Proline--tRNA ligase (Gene Name=proS)

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